anything that would replace CSS.

😣😣

Less, sass, make your pick.
(also, to be a real nitpicker, css is not for designing but for styling ;) )

Sass!

No. Not preprocessors.

I meant something that would remove the awful CSS way of laying out stuff (inline box, floats, margins, etc).

Something more friendly.
@LucaScorpion

@makkBit Ahh I see. How would you prefer to do it then? (genuine question 😁)

As long as we have flexboxes, I'm good

Adobe Corel Draw and img html tag element 😂 just kidding...

@divil
Yeah I think HTML in general is pretty uneffective to write and even more uneffective to read (at least when you have a lot of classes or attributes in one tag). Many say HAML is more effective but I haven't tried it so I can't tell. Like HTML comments, they are so written so ineffectively. Would have been alot better with the hash-symbol ( # ) or double slash ( // )

Flash! Java applets! 😈

Silverlight!

@PetriJ I think it's the abuse of classes that causes the issue.
People don't (know how to) use the 'cascading' part of CSS.

Bootstrap. V4 . Not much but will reduce a lot of effort.