I fucking hate Visual Studio!

Don't get me wrong, from time to time I actually enjoy it but not today.
It all went south when I tried to add a new handler to an fucking old asp.net webpage. I had the access the 'Range' headed to stream bits of audio and video files to the client. It was working absolutely fine for the first hour and a half, after that point the fun started...
VS decided that my source code and the binaries won't match anymore. Everytime I tried to add a fucking breakpoint or debug this cunt of an error it would just refuse
The worst part that made me go apeshit was when I finally got a breakpoint and the exception. Some unknown fucking system dll just kept on killing my thread without a proper error message because it's optimized to the fucking moon and back!

Any ideas from the devs here on what's going on and how the fuck I can fix this?