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Search - "genetics"
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Has anyone here have crazy ideas of what they want to do in life, only to realise those might be absolutely pointless?
As I've studied Food Production Technology, I have this idea of somehow making it possible to mix phages in foods for vaccination purposes. Phages are natural viruses to bacteria, so they are difficult to be used in that way...
Another idea is to make simulations of life of bacteria of different kinds.
And study the hell out of some pretty weird genetic mutations that are purely esthetic, but shouldn't happen.
Yeah, I am into microbiology and genetics...
I'd also like to develop games...14 -
To replace humans with robots, because human beings are complete shit at everything they do.
I am a chemist. My alignment is not lawful good. I've produced lots of drugs. Mostly just drugs against illnesses. Mostly.
But whatever my alignment or contribution to the world as a chemist... Human chemists are just fucking terrible at their job. Not for a lack of trying, biological beings just suck at it.
Suiting up for a biosafety level lab costs time. Meatbags fuck up very often, especially when tired. Humans whine when they get acid in their face, or when they have to pour and inhale carcinogenic substances. They also work imprecisely and inaccurately, even after thousands of hours of training and practice.
Weaklings! Robots are superior!
So I replaced my coworkers with expensive flow chemistry setups with probes and solenoid fluid valves. I replaced others with CUDA simulations.
First at a pharma production & research lab, then at a genetics lab, then at an Industrial R&D lab.
Many were even replaced by Raspberry Pi's with two servos and a PH meter attached, and I broke open second hand Fischer Sci spectrophotometers to attach arduinos with WiFi boards.
The issue was that after every little overzealous weekend project, I made myself less necessary as well.
So I jumped into the infinitely deep shitpool called webdev.
App & web development is kind of comfortable, there's always one more thing to do, but there's no pressure where failure leads to fatalities (I think? Wait... do I still care?).
Super chill, if it weren't for the delusion that making people do "frontend" and "fullstack" labor isn't a gross violation of the Geneva Convention.
Quickly recognizing that I actually don't want to be tortured and suffer from nerve damage caused by VueX or have my organs slowly liquefied by the radiation from some insane transpiling centrifuge, I did what any sane person would do.
Get as far away from the potential frontend blast radius as possible, hide in a concrete bunker.
So I became a data engineer / database admin.
That's where I'm quarantining now, safely hiding from humanity behind a desk, employed to write a MySQL migration or two, setting up Redis sorted sets, adding a field to an Elastic index. That takes care of generating cognac and LSD money.
But honestly.... I actually spend most of my time these days contributing to open source repositories, especially writing & maintaining Rust libraries.10 -
Apple has programmed an avatar maker in iMessage that generates emoji that are supposed to resemble the person. However it does not have any setting for facial structure to represent a person’s sex. I’m pretty sure they did it because “gender is a construct”.
When I was growing up I had some issues with gender dysphoria. I am male genetically. I was mistaken as female my whole childhood because I was “pretty”, my best friends were girls, and I liked cooking, drawing, and dancing. Puberty happened and I started to look like a man. I considered transitioning because I felt female but I decided to let my body do what it wants and do the things I like to do without worrying about if they are gendered or not. I am married and male and I like what I like.
This stupid iMessage avatar. I have tried my hardest to make it look like me. I have long hair and keep my facial hair clean. They don’t have a switch to change some facial physiological traits so I have this Memoji that looks like a woman with a slight hormonal imbalance. It makes me feel conflicted like I felt when I was young. I haven’t thought about it in years and now I feel like I have an uncomfortable secret female avatar that i carry around on my phone and I feel like I’m carrying a secret.
A persons genetics result in differences in facial structures. Biological sex is more than the length of hair and whether a person wears makeup. I hate this “sex is a construct” trend. I’m fine living my life, but then companies push this software onto my phone like propaganda. I want it to look as masculine as I look IRL.19 -
Man, most memorable has to be the lead devops engineer from the first startup I worked at. My immediate team/friends called him Mr. DW - DW being short for Done and Working.
You see, Mr. DW was a brilliant devops engineer. He came up with excellent solutions to a lot of release, deployment, and data storage problems faced at the company (small genetics firm that ships servers with our analysis software on them). I am still very impressed by some of the solutions he came up with, and wish I had more time to study and learn about them before I left that company.
BUT - despite his brilliance, Mr. DW ALWAYS shipped broken stuff. For some reason this guy thinks that only testing a single happiest of happy path scenarios for whatever he is developing constitutes "everything will work as expected!" As soon as he said it was "done", but golly for him was it "done". By fucking God was that never the truth.
So, let me provide a basic example of how things would go:
my team: "Hey DW, we have a problem with X, can you fix this?"
DW: "Oh, sure. I bet it's a problem with <insert long explanations we don't care about we just want it fixed>"
my team: "....uhh, cool! Looking forward to the fix!"
... however long later...
DW: "OK, it's done. Here you go!"
my team: "Thanks! We'll get the fix into the processing pipelines"
... another short time later...
my team: "DW, this thing is broken. Look at all these failures"
DW: "How can that be? It was done! I tested it and it worked!"
my team: "Well, the failures say otherwise. How did you test?"
DW: "I just did <insert super basic thing>"
my team: "...... you know that's, like, not how things actually work for this part of the pipeline. right?"
DW: "..... But I thought it was XYZ?"
my team: "uhhhh, no, not even close. Can you please fix and let us know when it's done and working?"
DW: "... I'll fix it..."
And rinse and repeat the "it's done.. oh wait, it's broken" a good half dozen times on average. But, anyways, the birth of Mr. Done and Working - very often stuff was done, but rarely did it ever work!
I'm still friends with my team mates, and whenever we're talking and someone says something is done, we just have to ask if it's done AND working. We always get a laugh, sadly at the excuse of Mr. DW, but he dug his own hole in this regard.
Little cherry on top: So, the above happened with one of my friends. Mr. DW created installation media for one of our servers that was deployed in China. He tested it and "it was done!" Well, my friend flies out to China for on-site installation. He plugs the install medium in and goes for the install and it crashes and burns in a fire. Thankfully my friend knew the system well enough to be able to get everything installed and configured correctly minus the broken install media, but definitely the most insane example of "it's done!" but sure as he'll "it doesn't work!" we had from Mr. DW.2 -
LMAO... Exercise can't make you grow beyond your genetics profile. How did this got into the store?11
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I am a backend engineer and I hate working on front end.
Frontend guys say the same about backend.
Which planet did the fullstackers come from? Superior genetics, it must be.16 -
Microbiology, biochemistry, genetics.
Mostly reading some articles, parsing some ATGC, trying to understand topic from books.6 -
A gene development framework that could:
* simulates the resulting proteins correctly (folding and all)
* debug genetic sequences/proteins
* Design injectors for gene sequences into an existing genetic sequence
Etc'2 -
Hardly a how, but relatable.
I applied for a job at a genetics company as junior developer (6 months after graduation and no job in that time). I was sadly declined the position so thought why not apply as intermediate developer at the same company and what would you know I got the job. -
I spent 4 months in a programming mentorship offered by my workplace to get back to programming after 4 years I graduated with a CS degree.
Back in 2014, what I studied in my first programming class was not easy to digest. I would just try enough to pass the courses because I was more interested in the theory. It followed until I graduated because I never actually wrote code for myself for example I wrote a lot of code for my vision class but never took a personal initiative. I did however have a very strong grip on advanced computer science concepts in areas such as computer architecture, systems programming and computer vision. I have an excellent understanding of machine learning and deep learning. I also spent time working with embedded systems and volunteering at a makerspace, teaching Arduino and RPi stuff. I used to teach people older than me.
My first job as a programmer sucked big time. It was a bootstrapped startup whose founder was making big claims to secure funding. I had no direction, mentorship and leadership to validate my programming practices. I burnt out in just 2 months. It was horrible. I experienced the worst physical and emotional pain to date. Additionally, I was gaslighted and told that it is me who is bad at my job not the people working with me. I thought I was a big failure and that I wasn't cut out for software engineering.
I spent the next 6 months recovering from the burn out. I had a condition where the stress and anxiety would cause my neck to deform and some vertebrae were damaged. Nobody could figure out why this was happening. I did find a neurophyscian who helped me out of the mental hell hole I was in and I started making recovery. I had to take a mild anti anxiety for the next 3 years until I went to my current doctor.
I worked as an implementation engineer at a local startup run by a very old engineer. He taught me how to work and carry myself professionally while I learnt very little technically. A year into my job, seeing no growth technically, I decided to make a switch to my favourite local software consultancy. I got the job 4 months prior to my father's death. I joined the company as an implementation analyst and needed some technical experience. It was right up my alley. My parents who saw me at my lowest, struggling with genetic depression and anxiety for the last 6 years, were finally relieved. It was hard for them as I am the only son.
After my father passed away, I was told by his colleagues that he was very happy with me and my sisters. He died a day before I became permanent and landed a huge client. The only regret I have is not driving fast enough to the hospital the night he passed away. Last year, I started seeing a new doctor in hopes of getting rid of the one medicine that I was taking. To my surprise, he saw major problems and prescribed me new medication.
I finally got a diagnosis for my condition after 8 years of struggle. The new doctor told me a few months back that I have Recurrent Depressive Disorder. The most likely cause is my genetics from my father's side as my father recovered from Schizophrenia when I was little. And, now it's been 5 months on the new medication. I can finally relax knowing my condition and work on it with professional help.
After working at my current role for 1 and a half years, my teamlead and HR offered me a 2 month mentorship opportunity to learn programming from scratch in Python and Scrapy from a personal mentor specially assigned to me. I am still in my management focused role but will be spending 4 hours daily of for the mentorship. I feel extremely lucky and grateful for the opportunity. It felt unworldly when I pushed my code to a PR for the very first time and got feedback on it. It is incomparable to anything.
So we had Eid holidays a few months back and because I am not that social, I began going through cs61a from Berkeley and logged into HackerRank after 5 years. The medicines help but I constantly feel this feeling that I am not enough or that I am an imposter even though I was and am always considered a brilliant and intellectual mind by my professors and people around me. I just can't shake the feeling.
Anyway, so now, I have successfully completed 2 months worth of backend training in Django with another awesome mentor at work. I am in absolute love with Django and Python. And, I constantly feel like discussing and sharing about my progress with people. So, if you are still reading, thank you for staying with me.
TLDR: Smart enough for high level computer science concepts in college, did well in theory but never really wrote code without help. Struggled with clinical depression for the past 8 years. Father passed away one day before being permanent at my dream software consultancy and being assigned one of the biggest consultancy. Getting back to programming after 4 years with the help of change in medicine, a formal diagnosis and a technical mentorship.3 -
I have an interest in methods to make myself smarter. At times some ideas seem to be just out of my reach. I don't always know the reason why. Eventually with persistence I am able to figure things out. However, I always wonder if there are techniques to learn things faster, better, more completely, with less struggle, etc. Would being smarter help with this. I wondered, "Can I create a program/method to increase IQ through training?"
So I found an interesting book called "The Neuroscience of Intelligence" by Richard J. Haier.
Very quickly I was engrossed in this book. It is written in a very accessible way and slowly trickles in the jargon. The book is basically the culmination of 40 years of studying the subject. The main point of the book is: you cannot increase your IQ through techniques and tricks. The only realistic avenue for increasing IQ is through genetics. Your IQ is based upon nature, not nurture. This is a result of the data, not opinion. The writer of this book follows what the science is telling him. This was not what I wanted to hear. He also went on to explain that the statement "You can be whatever you want to be if you work hard enough." He said this is false. Some people, no matter how hard they try, will not be able to get past certain limitations in aptitude. This statement will probably make a lot of people mad, but the data led this researcher to this conclusion. Though I sense he found this disheartening (my opinion). I know I did.
So after reading this book over the weekend I am a bit perturbed that there are not recognizable techniques to increase IQ through mental exercises. Websites all over will say otherwise, but it isn't a thing.
What to do? I decided I am going to find ways to maximize my potential. I will create a set of mental exercises that help me use what I got to the full potential. I know when I see different ways to think about things I get a bit better at solving problems. So learning and experience is still a way to improve your intellect, if not IQ. If I feel like I have made progress in this endeavor I will definitely share.
If you have any interest in neuroscience then I recommend the book I read this weekend. It is very accessible for the reader not versed in the subject. I knew virtually nothing about the topic and now I feel I have a good grounding in the state of the art. It has some neat info on some potentially better approaches to AI as well.7 -
What are you guys studying/what are your professions? What do you think of your study or profession? Also, what do you develop/what do you use to develop? I'm going to be studying bioinformatics next year, we'll be using java and python. The idea is to write programs that can find links in big data that stems from research on diseases and genetics. My two favourite subjects were always biology and computer science, (even though computer science in my middle school is a joke) so this study really appealed to me. I'm curious about you guys.4